The Eric and Wendy Schmidt Center Symposium on Biomedical Science and AI
Wednesday, April 30 and Thursday, May 1, 2025 in Cambridge, MA

‍Bringing together researchers who develop the foundations of machine learning and apply the resulting methods to understand the programs of life and how they connect across scales - from proteins to cells to tissues and organisms. 

Experts in the field will discuss how machine learning is revealing important insights into the most pressing biomedical questions of our time and, conversely, how these biomedical questions are driving foundational advances in machine learning.

Wednesday, April 30

8:00 - 8:40 am -- Registration and breakfast

8:40 - 8:50 am -- Opening remarks

Todd Golub, Director of Broad Institute, Founding Core Institute Member

8:50 - 9:00 am -- Schmidt Center Introduction

Caroline Uhler, Director, Eric and Wendy Schmidt Center

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9:00 - 9:30 am -- Plenary talk

Jennifer Lippincot-Schwartz, Howard Hughes Medical Institute's Janelia Research Campus

9:30 - 10:00 am -- Plenary talk

Michael Bronstein, University of Oxford / Aithyra Institute

10:00 - 10:15 am -- Plenary talk

Speaker selected from submitted abstracts

10:15 - 10:30 am -- Plenary talk

Speaker selected from submitted abstracts

10:30 - 11:00 am -- Coffee break

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11:00 - 11:30 am -- Foundation models for biology, across scales

Jean-Philippe Vert, Owkin & Bioptimus

11:30 am - 12:00 pm -- Toward a holistic and quantitative stem cell state landscape

Susanne Rafelski, Allen Institute for Cell Science

12:00 - 12:30 pm -- Flash talks

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12:30 - 2:00 pm -- Lunch and poster session

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2:00 - 2:30 pm -- Genomes & AI: from Packing to Regulation

GV Shivashankar, ETH Zurich

2:30 - 3:00 pm -- Plenary talk

Dana Pe'er, Memorial Sloan Kettering Cancer Center

3:00 - 3:15 pm -- Plenary talk

Speaker selected from submitted abstracts

3:15 - 3:30 pm -- Plenary talk

Speaker selected from submitted abstracts

3:30 - 4:00 pm -- Coffee break

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4:00 - 5:30 pm -- Panel discussion on Novel large-scale data creation: Genomes, Cells, Tissues, Organisms

Fei Chen, Broad Institute

Anne Carpenter, Broad Institute

Mark Daly, Broad Institute

Xiaowei Zhuang, Harvard University

Moderator: Eric Lander, Broad Institute

5:30 pm -- Closing remarks

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Thursday, May 1

8:30 - 9:00 am -- Registration and breakfast

9:00 - 9:30 am -- Computational challenges in functional genomics

John Marioni, Genentech - Roche

9:30 - 10:00 am -- Decoding human cell and tissue architectures - from spatial proteomics to whole cell modelling

Emma Lundberg, Stanford University

10:00 - 10:15 am -- Plenary talk

Speaker selected from submitted abstracts

10:15 - 10:30 am -- Plenary talk

Speaker selected from submitted abstracts

10:30 - 11:00 am -- Coffee break

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11:00 - 11:30 am -- Plenary talk

Maria Brbic, EPFL

11:30 am - 12:00 pm -- Deep learning the cis-regulatory code at single base and single cell resolution

Anshul Kundaje, Dept. of Genetics, Dept. of Computer Science, Stanford University

12:00 - 12:30 pm -- Flash talks

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12:30 - 2:00 pm -- Lunch and poster session

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2:00 - 2:30 pm -- Toward AI-Driven Digital Organism: Multiscale Foundation Models for Predicting, Simulating, and Programming Biology at All Levels

Eric Xing, GenBio AI, CMU, MBZUAI

2:30 - 3:00 pm -- Plenary talk

Patrick Hsu, Arc Institute, UC Berkeley

3:00 - 3:15 pm -- Plenary talk

Speaker selected from submitted abstracts

3:15 - 3:30 pm -- Plenary talk

Speaker selected from submitted abstracts

3:30 - 4:00 pm -- Coffee break

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4:00 - 5:30 pm -- Panel Discussion on Foundation models in biology: DNA, Protein, Cells, Tissues, Organisms

Faisal Mahmood, Harvard Division of Medical Sciences

Shirley Liu, GV20 Therapeutics

Marzyeh Ghassemi, MIT

Moderator: Caroline Uhler, Broad Institute

5:30 pm -- Closing remarks

Please register through Eventbrite.